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Distinct signals in medial and lateral VTA dopamine neurons modulate fear extinction at different times

Dopamine (DA) neurons are thought to encode reward prediction error (RPE), in addition to other signals, such as salience. While RPE is known to support learning, the role of salience in learning remains less clear. To address this, we recorded and manipulated VTA DA neurons in mice during fear exti...

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Autori principali: Lili X Cai, Katherine Pizano, Gregory W Gundersen, Cameron L Hayes, Weston T Fleming, Sebastian Holt, Julia M Cox, Ilana B Witten
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications Ltd 2020-06-01
Serie:eLife
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Accesso online:https://elifesciences.org/articles/54936
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