Efficacy and safety of sini powder combined with Xiaoxianxiong decoction for adolescent depression with liver qi stagnation and phlegm-heat obstruction syndrome: a randomized controlled trial

ObjectiveTo assess efficacy and safety of Sini San combined with Xiaoxianxiong Tang as add-on therapy for adolescents (12–18 years) with liver qi stagnation and phlegm-heat depression, and to provide preliminary evidence for TCM syndrome-based treatment.MethodsSixty adolescents (12–18 years) with mo...

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Autores principales:	Ruiyu Lin, Yangzhen Liu, Juncheng Li, Jia Gao, Liting He, Shanying Huang
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2026-06-01
Colección:	Frontiers in Pediatrics
Materias:	add-on therapy adolescent depression Chinese medicinal compound clinical efficacy liver qi stagnation phlegm-heat blocking the middle energizer
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fped.2026.1787781/full
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