A platinum(IV) prodrug strategy to overcome glutathione-based oxaliplatin resistance
Platinum(IV) complexes have the potential to overcome several limitations and reduce adverse effects of platinum-based cancer therapy. Resistance to clinically approved platinum(II) drugs is, at least in part, associated with elevated levels of glutathione. Here, the authors report on an oxaliplatin...
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| Principais autores: | , , , , , , , , , |
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| 格式: | Artigo |
| 语言: | Inglês |
| 出版: |
Nature Portfolio
2022-04-01
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| 丛编: | Communications Chemistry |
| 在线阅读: | https://doi.org/10.1038/s42004-022-00661-z |
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