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Non-coding variants in VAMP2 and SNAP25 affect gene expression: potential implications in migraine susceptibility

Abstract Migraine is a common and complex neurological disease potentially caused by a polygenic interaction of multiple gene variants. Many genes associated with migraine are involved in pathways controlling the synaptic function and neurotransmitters release. However, the molecular mechanisms unde...

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Autori principali: Daniela Felício, Andreia Dias, Sandra Martins, Estefânia Carvalho, Alexandra M. Lopes, Nádia Pinto, Carolina Lemos, Mariana Santos, Miguel Alves-Ferreira
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2023-06-01
Serie:The Journal of Headache and Pain
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Accesso online:https://doi.org/10.1186/s10194-023-01615-z
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