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Selective constraint on the upstream open reading frames that overlap with coding sequences in animals.

Upstream open reading frames (uORFs) are translational regulatory elements located in 5' untranslated regions. They can significantly repress the translation of the downstream coding sequences (CDS), and participate in the spatio-temporal regulations of protein translation. Notwithstanding this biol...

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Principais autores: Ming-Kung Hsu, Feng-Chi Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2012-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3486843?pdf=render
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