Cell line-matched reference enables high-precision functional genomics
Abstract Comparative analyses of newly available human genome assemblies highlight extensive variation that peaks at centromeres. Reliance on a single generic reference genome can thus hinder whole-genome analysis of sequencing data derived from laboratory cell lines and limit their accurate genomic...
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| Principais autores: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Portfolio
2025-11-01
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| Serier: | Nature Communications |
| Online adgang: | https://doi.org/10.1038/s41467-025-66155-3 |
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