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Genomic risk prediction of type 2 diabetes in people living with and without HIV

Abstract Type 2 diabetes (T2D) risk prediction remains a challenge, particularly in underrepresented populations, including people living with HIV (PWH) and those of non-European ancestry. We evaluated the performance of two metaPRS (polygenic risk score) models, integrating genetic markers related...

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Furkejuvvon:
Váldodahkkit: Nicole D. Armstrong, Vinodh Srinivasasainagendra, Lavanya Pilla, Radhika Gangaraju, Peter W. Hunt, Robin M. Nance, Heidi M. Crane, Inga Peter, Sonya L. Heath, Greer A. Burkholder, Richard D. Moore, Jeffrey M. Jacobson, Edward R. Cachay, Thibaut Davy-Mendez, Hirotaka Iwaki, Lana Sargent, Hemant K. Tiwari, Marguerite R. Irvin
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Nature Portfolio 2026-01-01
Ráidu:Scientific Reports
Fáttát:
Polygenic risk score
Precision medicine
Type 2 diabetes
HIV
Liŋkkat:https://doi.org/10.1038/s41598-025-31471-7
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