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Scoring Thoracic CT Scans of Patients with NFKB1-Related Disease for Clinical Management and Treatment Studies Using Four Parameters (Adapted from the Hartmann Score)

BackgroundNFKB1 encodes the p105/p50 nuclear factor-kappa-B (NF-κB1) transcription factor. Heterozygous mutations in NFKB1 are associated with NFKB1-related disease, including granulomatous-lymphocytic interstitial lung disease (GLILD) or similar lung involvement. We aimed to characterize and score...

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Main Authors: Katharina Thoma, Manfred Fliegauf, Bärbel Keller, Maximilian Frederik Russe, Gabriele Müller, Michele Proietti, Andres Caballero Garcia de Oteyza, Pavla Mrovecova, Helene Kraus, Klaus Warnatz, Nadezhda Camacho Ordonez, Aleksandra Hirsch, Christoph Geier, Máté Krausz, Sigune Goldacker, Natalie Frede, Stephan Ehl, Sarah Salou, Shahrzad Bakhtiar, Maria Fasshauer, Michael Borte, Oliver Hausmann, Faranaz Atschekzei, Georgios Sogkas, Ansgar Schulz, Bodo Grimbacher, Prerana Agarwal
Format: Artigo
Language:Inglês
Published: Rockefeller University Press 2026-05-01
Series:Journal of Human Immunity
Online Access:https://rupress.org/jhi/article/2/CIS2026/eCIS2026abstract.96/281843/Scoring-Thoracic-CT-Scans-of-Patients-with-NFKB1
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