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Mitochondria and Doxorubicin-Induced Cardiomyopathy: A Complex Interplay

Cardiotoxicity has emerged as a major side effect of doxorubicin (DOX) treatment, affecting nearly 30% of patients within 5 years after chemotherapy. Heart failure is the first non-cancer cause of death in DOX-treated patients. Although many different molecular mechanisms explaining the cardiac dera...

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Principais autores: Leonardo Schirone, Luca D’Ambrosio, Maurizio Forte, Riccardo Genovese, Sonia Schiavon, Giulia Spinosa, Giuliano Iacovone, Valentina Valenti, Giacomo Frati, Sebastiano Sciarretta
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-06-01
Serier:Cells
Fag:
DOX
anthracycline
cardiomyopathy
mitochondria
heart
Online adgang:https://www.mdpi.com/2073-4409/11/13/2000
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