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Vibrio cholerae O1 experiences mild bottlenecks through the gastrointestinal tract in some but not all cholera patients

ABSTRACT Vibrio cholerae O1 causes the diarrheal disease cholera, and the small intestine is the site of active infection. During cholera, cholera toxin is secreted from V. cholerae and induces a massive fluid influx into the small intestine, which causes vomiting and diarrhea. Typically, V. cholera...

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Автори: Patrick Lypaczewski, Denise Chac, Chelsea N. Dunmire, Kristine M. Tandoc, Fahima Chowdhury, Ashraful I. Khan, Taufiqur R. Bhuiyan, Jason B. Harris, Regina C. LaRocque, Stephen B. Calderwood, Edward T. Ryan, Firdausi Qadri, B. Jesse Shapiro, Ana A. Weil
Формат: Artigo
Мова:Inglês
Опубліковано: American Society for Microbiology 2024-08-01
Серія:Microbiology Spectrum
Предмети:
cholera
whole-genome sequencing
comparative genomics
single-nucleotide variants
Vibrio cholerae
vomit
Онлайн доступ:https://journals.asm.org/doi/10.1128/spectrum.00785-24
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