Human Regulatory T Cells From Umbilical Cord Blood Display Increased Repertoire Diversity and Lineage Stability Relative to Adult Peripheral Blood

The human T lymphocyte compartment is highly dynamic over the course of a lifetime. Of the many changes, perhaps most notable is the transition from a predominantly naïve T cell state at birth to the acquisition of antigen-experienced memory and effector subsets following environmental exposures. Th...

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Detalhes bibliográficos

Principais autores:	Keshav Motwani, Leeana D. Peters, Willem H. Vliegen, Ahmed Gomaa El-sayed, Howard R. Seay, M. Cecilia Lopez, Henry V. Baker, Amanda L. Posgai, Maigan A. Brusko, Daniel J. Perry, Rhonda Bacher, Joseph Larkin, Michael J. Haller, Todd M. Brusko
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2020-04-01
coleção:	Frontiers in Immunology
Assuntos:	cord blood peripheral blood regulatory T cells Tregs adoptive cell therapy scRNA-seq
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fimmu.2020.00611/full
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