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Ketoconazole- and fluconazole-induced embryotoxicity and skeletal anomalies in wistar rats: a comparative study

Ketoconazole and fluconazole are two broad-spectrum azole antifungals used for the treatment of superficial and systemic mycoses. Embryotoxicity and teratogenicity have been reported in some studies when those drugs are administered at high doses to pregnant rats. The aim of this study was to presen...

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Hlavní autoři: Vanessa Cristiane de Santana Amaral, Guilhermino Pereira Nunes Junior
Médium: Artigo
Jazyk:Inglês
Vydáno: Instituto de Tecnologia do Paraná (Tecpar) 2008-12-01
Edice:Brazilian Archives of Biology and Technology
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On-line přístup:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000600010
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