Targeting MCL-1 protein to treat cancer: opportunities and challenges
Evading apoptosis has been linked to tumor development and chemoresistance. One mechanism for this evasion is the overexpression of prosurvival B-cell lymphoma-2 (BCL-2) family proteins, which gives cancer cells a survival advantage. Mcl-1, a member of the BCL-2 family, is among the most frequently...
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| Huvudupphov: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
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Frontiers Media S.A.
2023-07-01
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| Serie: | Frontiers in Oncology |
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| Länkar: | https://www.frontiersin.org/articles/10.3389/fonc.2023.1226289/full |
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