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GPR43 alleviates LPS-induced acute lung injury by inhibiting NLRP3 inflammasome activation via β-arrestin 2

Abstract Background Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are severe respiratory ailments globally, with the NLRP3 inflammasome playing a crucial role in the progression of ALI. G protein-coupled receptor 43 (GPR43) plays a role in regulating the immune system and ma...

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Bibliografske podrobnosti
Principais autores: Changli Wang, Wangzheqi Zhang, Yu Guo, Yan Liao, Na Li, Yan Zhang, Lulong Bo, Jinjun Bian, Jia-feng Wang
Format: Artigo
Jezik:Inglês
Izdano: BMC 2026-01-01
Serija:Biology Direct
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Online dostop:https://doi.org/10.1186/s13062-025-00725-9
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