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Radiation-induced CD8 T-lymphocyte Apoptosis as a Predictor of Breast Fibrosis After Radiotherapy: Results of the Prospective Multicenter French Trial

Background: Monocentric cohorts suggested that radiation-induced CD8 T-lymphocyte apoptosis (RILA) can predict late toxicity after curative intent radiotherapy (RT). We assessed the role of RILA as a predictor of breast fibrosis (bf+) after adjuvant breast RT in a prospective multicenter trial. Meth...

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Principais autores: David Azria, Olivier Riou, Florence Castan, Tan Dat Nguyen, Karine Peignaux, Claire Lemanski, Jean-Léon Lagrange, Youlia Kirova, Eric Lartigau, Yazid Belkacemi, Céline Bourgier, Sofia Rivera, Georges Noël, Sébastien Clippe, Françoise Mornex, Christophe Hennequin, Andrew Kramar, Sophie Gourgou, André Pèlegrin, Pascal Fenoglietto, Esat Mahmut Ozsahin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015-12-01
coleção:EBioMedicine
Assuntos:
Apoptosis
Lymphocyte
Radiotherapy
Breast fibrosis
Prediction
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2352396415301869
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