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Distinct Contribution of the HtrA Protease and PDZ Domains to Its Function in Stress Resilience and Virulence of Bacillus anthracis

Anthrax is a lethal disease caused by the Gram-positive spore-producing bacterium Bacillus anthracis. We previously demonstrated that disruption of htrA gene, encoding the chaperone/protease HtrABA (High Temperature Requirement A of B. anthracis) results in significant virulence attenuation, despite...

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Bibliografiska uppgifter
Huvudupphov: Ma’ayan Israeli, Uri Elia, Shahar Rotem, Hila Cohen, Avital Tidhar, Adi Bercovich-Kinori, Ofer Cohen, Theodor Chitlaru
Materialtyp: Artigo
Språk:Inglês
Utgiven: Frontiers Media S.A. 2019-02-01
Serie:Frontiers in Microbiology
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Länkar:https://www.frontiersin.org/article/10.3389/fmicb.2019.00255/full
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