Transcutaneous penetration of a single-chain variable fragment (scFv) compared to a full-size antibody: potential tool for atopic dermatitis (AD) treatment

Abstract Currently, several biologics are used for the treatment of cutaneous pathologies such as atopic dermatitis (AD), psoriasis or skin cancers. The main administration routes are subcutaneous and intravenous injections. However, little is known about antibody penetration through the skin. The a...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Audrey Baylet, Raoul Vyumvuhore, Marine Laclaverie, Laëtitia Marchand, Carine Mainzer, Sylvie Bordes, Brigitte Closs-Gonthier, Laurent Delpy
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2021-07-01
coleção:	Allergy, Asthma & Clinical Immunology
Assuntos:	Transcutaneous penetration Single-chain variable fragment Antibody Atopic dermatitis
Acesso em linha:	https://doi.org/10.1186/s13223-021-00574-x
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!