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Neutralization diversity of HIV-1 Indian subtype C envelopes obtained from cross sectional and followed up individuals against broadly neutralizing monoclonal antibodies having distinct gp120 specificities

Abstract Background The potential use of the broadly neutralizing monoclonal antibodies (bnAbs) towards prophylaxis and treatment to HIV-1 is currently being explored. While a number of promising bnAbs have been discovered and a few of them have progressed towards clinical development, their extent...

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Principais autores: Ranajoy Mullick, Jyoti Sutar, Nitin Hingankar, Suprit Deshpande, Madhuri Thakar, Seema Sahay, Rajesh P. Ringe, Sampurna Mukhopadhyay, Ajit Patil, Shubhangi Bichare, Kailapuri G. Murugavel, Aylur K. Srikrishnan, Rajat Goyal, Devin Sok, Jayanta Bhattacharya
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2021-05-01
coleção:Retrovirology
Assuntos:
HIV-1
Clade C
Neutralizing antibodies
Envelope
VRC01
CAP256-VRC26.25
Acesso em linha:https://doi.org/10.1186/s12977-021-00556-2
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