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The acid-base-nucleophile catalytic triad in ABH-fold enzymes is coordinated by a set of structural elements.

The alpha/beta-Hydrolases (ABH) are a structural class of proteins that are found widespread in nature and includes enzymes that can catalyze various reactions in different substrates. The catalytic versatility of the ABH fold enzymes, which has been a valuable property in protein engineering applic...

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Hlavní autoři: Alexander Denesyuk, Polytimi S Dimitriou, Mark S Johnson, Toru Nakayama, Konstantin Denessiouk
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2020-01-01
Edice:PLoS ONE
On-line přístup:https://doi.org/10.1371/journal.pone.0229376
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