SonicParanoid2: fast, accurate, and comprehensive orthology inference with machine learning and language models

Abstract Accurate inference of orthologous genes constitutes a prerequisite for comparative and evolutionary genomics. SonicParanoid is one of the fastest tools for orthology inference; however, its scalability and accuracy have been hampered by time-consuming all-versus-all alignments and the exist...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Salvatore Cosentino, Sira Sriswasdi, Wataru Iwasaki
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2024-07-01
Schriftenreihe:	Genome Biology
Schlagworte:	Orthology inference Machine learning Language model Genome evolution
Online-Zugang:	https://doi.org/10.1186/s13059-024-03298-4
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