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A surge in serum mucosal cytokines associated with seroconversion in children at risk for type 1 diabetes

ABSTRACT Aims/Introduction Autoantibodies to pancreatic islet antigens identify young children at high risk of type 1 diabetes. On a background of genetic susceptibility, islet autoimmunity is thought to be driven by environmental factors, of which enteric viruses are prime candidates. We sought evi...

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Principais autores: Leonard C Harrison, Esther Bandala‐Sanchez, Helena Oakey, Peter G Colman, Kelly Watson, Ki Wook Kim, Roy Wu, Emma E Hamilton‐Williams, Natalie L Stone, Aveni Haynes, Rebecca L Thomson, Peter J Vuillermin, Georgia Soldatos, William D Rawlinson, Kelly J McGorm, Grant Morahan, Simon C Barry, Richard O Sinnott, John M Wentworth, Jennifer J Couper, Megan AS Penno, the ENDIA Study Group
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2023-09-01
coleção:Journal of Diabetes Investigation
Assuntos:
Islet autoantibody
Seroconversion
Serum cytokine
Acesso em linha:https://doi.org/10.1111/jdi.14031
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