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The adjuvants dmLT and mmCT enhance humoral immune responses to a pneumococcal conjugate vaccine after both parenteral or mucosal immunization of neonatal mice

Immaturity of the neonatal immune system contributes to increased susceptibility to infectious diseases and poor vaccine responses. Therefore, better strategies for early life vaccination are needed. Adjuvants can enhance the magnitude and duration of immune responses. In this study we assessed the...

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Autori principali: Jenny Lorena Molina Estupiñan, Audur Anna Aradottir Pind, Poorya Foroutan Pajoohian, Ingileif Jonsdottir, Stefania P. Bjarnarson
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2023-01-01
Serie:Frontiers in Immunology
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Accesso online:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1078904/full
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