Hydrophilic bile acids protect human blood-brain barrier endothelial cells from disruption by unconjugated bilirubin: an in vitro study

Ursodeoxycholic acid and its main conjugate glycoursodeoxycholic acid are bile acids with neuroprotective properties. Our previous studies demonstrated their anti-apoptotic, anti-inflammatory and antioxidant properties in neural cells exposed to elevated levels of unconjugated bilirubin as in sever...

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Bibliografiske detaljer

Principais autores:	Inês ePalmela, Leonor eCorreia, Rui eSilva, Hiroyuki eSasaki, Kwang Sik Kim, Dora eBrites, Maria A Brito
Format:	Artigo
Sprog:	Inglês
Udgivet:	Frontiers Media S.A. 2015-03-01
Serier:	Frontiers in Neuroscience
Fag:	Blood-Brain Barrier Interleukin-6 Unconjugated bilirubin Glycoursodeoxycholic acid Human brain microvascular endothelial cells ursodeoxycholic acid.
Online adgang:	http://journal.frontiersin.org/Journal/10.3389/fnins.2015.00080/full
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