Structural basis for the tryptophan sensitivity of TnaC-mediated ribosome stalling

Bacteria adjust the expression of some of their metabolic enzymes through metabolite-sensing ribosome nascent chain complexes. Here the authors present a cryo-EM structure of an E. coli ribosome stalled during translation of the TnaC leader peptide and propose a model for L-Trp dependent ribosome st...

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Autori principali:	Anne-Xander van der Stel, Emily R. Gordon, Arnab Sengupta, Allyson K. Martínez, Dorota Klepacki, Thomas N. Perry, Alba Herrero del Valle, Nora Vázquez-Laslop, Matthew S. Sachs, Luis R. Cruz-Vera, C. Axel Innis
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2021-09-01
Serie:	Nature Communications
Accesso online:	https://doi.org/10.1038/s41467-021-25663-8
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