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Biologically-constrained spiking neural network for neuromodulation in locomotor recovery after spinal cord injury.

Presynaptic inhibition after spinal cord injury (SCI) has been hypothesised to disproportionately affect flexion reflex loops in locomotor spinal circuitry. Reducing gamma-aminobutyric acid (GABA) inhibitory activity increases the excitation of flexion circuits, restoring muscle activation and stepp...

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Autors principals: Raymond Chia, Chin-Teng Lin
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2026-01-01
Col·lecció:PLoS Computational Biology
Accés en línia:https://doi.org/10.1371/journal.pcbi.1013866
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