Epigenetic reprogramming in mouse and human primordial germ cells
Abstract Primordial germ cells (PGCs) are the precursors of sperm and eggs. They undergo genome-wide epigenetic reprogramming to erase epigenetic memory and reset the genomic potential for totipotency. Global DNA methylation erasure is a crucial part of epigenetic resetting when DNA methylation leve...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
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Nature Publishing Group
2024-12-01
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| Edice: | Experimental and Molecular Medicine |
| On-line přístup: | https://doi.org/10.1038/s12276-024-01359-z |
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