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High fat diet altered cardiac metabolic gene profile in Psammomys obesus gerbils

Abstract Background In metabolic disorders, myocardial fatty infiltration is critically associated with lipotoxic cardiomyopathy. Methods Twenty Psammomys obesus gerbils were randomly assigned to normal plant or high fat diet. Sixteen weeks later, myocardium was sampled for pathobiological evaluatio...

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Principais autores: Abdelhamid Sahraoui, Céline Dewachter, Grégory Vegh, Kathleen Mc Entee, Robert Naeije, Souhila Aouichat Bouguerra, Laurence Dewachter
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2020-06-01
Serier:Lipids in Health and Disease
Fag:
Lipotoxicity
Psammomys obesus
High fat diet
Cardiomyopathy
Apoptosis
Online adgang:http://link.springer.com/article/10.1186/s12944-020-01301-y
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