Lentivirus-Mediated Trophoblast-Specific Deptor Knockdown Increases Transplacental System A and System L Amino Acid Transport and Fetal Growth in Mice

Abstract Mechanistic target of rapamycin (mTOR) signaling is a positive regulator of human placental function including system A/L amino acid transport activity. Placental mTOR signaling is inhibited in fetal growth restriction (FGR) and activated in fetal overgrowth in women; however, the causes of...

Olles dieđut

Bibliográfalaš dieđut

Váldodahkkit:	Avery Kramer, Owen R Vaughan, Kenneth Barentsen, Johann Urschitz, Theresa L Powell, Thomas Jansson, Fredrick J Rosario
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	American Physiological Society 2025-01-01
Ráidu:	Function
Fáttát:	placenta maternal-fetal exchange system A system L mechanistic target of rapamycin fetal development
Liŋkkat:	https://journals.physiology.org/doi/10.1093/function/zqaf018
Fáddágilkorat:	Lasit fáddágilkoriid Eai fáddágilkorat, Lasit vuosttaš fáddágilkora!