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Some variables affecting the characteristics of Eudragit E-sodium alginate polyelectrolyte complex as a tablet matrix for diltiazem hydrochloride

Eudragit E (EE)-sodium alginate (SA) polyelectrolyte complexes (PECs) were prepared at pH 4 and 5.8 using sodium alginate of high (SAH) and low viscosity (SAL). The optimum EE-SA complexation mass ratio was determined using viscosity measurements. Interactions between EE and SA in PECs were characte...

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Principais autores: Yusif Rehab Mohammad, Hashim Irhan Ibrahim Abu, El-Dahan Marwa Salah
Format: Artigo
Sprog:Inglês
Udgivet: Sciendo 2014-03-01
Serier:Acta Pharmaceutica
Fag:
polyelectrolyte complex
diltiazem hydrochloride
Eudragit E 100
sodium alginate
viscosity
tablet matrix
Online adgang:http://www.degruyter.com/view/j/acph.2014.64.issue-1/acph-2014-0010/acph-2014-0010.xml?format=INT
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