Hydrophobic Modification of Poly(γ-glutamic acid) by Grafting 4-Phenyl-butyl Side Groups for the Encapsulation and Release of Doxorubicin

The delivery of drugs is a great challenge, since most of active pharmaceutical ingredients developed today are hydrophobic and poorly water soluble. From this perspective, drug encapsulation on biodegradable and biocompatible polymers can surpass this problem. Poly(γ-glutamic acid) (PGGA), a bioedi...

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Hlavní autoři:	Porochista Dorost, Montserrat García-Alvarez, Antxon Martínez de Ilarduya
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2023-04-01
Edice:	Pharmaceutics
Témata:	poly(γ-glutamic acid) biodegradable nanoparticles drug delivery nanoparticles doxorubicin drug encapsulation pH-responsive drug delivery
On-line přístup:	https://www.mdpi.com/1999-4923/15/5/1377
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