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An Ex Vivo Intervertebral Disc Slice Culture Model for Studying Disc Degeneration and Immune Cell Interactions

Intervertebral disc degeneration is a leading cause of back and leg pain and a major contributor to disability worldwide. Despite its prevalence, treatments remain limited due to incomplete understanding of its pathology. In vivo models pose challenges for controlled conditions, while in vitro cell...

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Principais autores: Eunha G. Oh, Li Xiao, Zhiwen Xu, Yuan Xing, Yi Zhang, Parastoo Anbaei, Jialun A. Chi, Li Jin, Rebecca R. Pompano, Xudong Li
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2025-08-01
סדרה:Cells
נושאים:
intervertebral discs
disc degeneration
tissue slice
macrophages
back pain
גישה מקוונת:https://www.mdpi.com/2073-4409/14/16/1230
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