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5-ALA-mediated fluorescence of musculoskeletal tumors in a chick chorio-allantoic membrane model: preclinical in vivo qualification analysis as a fluorescence-guided surgery agent in Orthopedic Oncology

Abstract Background Fluorescence-guided surgery (FGS) with 5-aminolevulinic acid (5-ALA) and other contrast agents has shown its efficacy in improving resection margins, local recurrence and survival rates in several medical disciplines. It is the objective of this study to analyze the engraftment r...

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Kaydedildi:
Asıl Yazarlar: Wiebke K. Guder, Wolfgang Hartmann, Clarissa Buhles, Maike Burdack, Maike Busch, Nicole Dünker, Jendrik Hardes, Uta Dirksen, Sebastian Bauer, Arne Streitbürger
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2022-01-01
Seri Bilgileri:Journal of Orthopaedic Surgery and Research
Konular:
Musculoskeletal tumor
Sarcoma
5-Aminolevulinic acid
Chick chorio-allantoic membrane model
Tumor fluorescence
Photodynamic detection
Online Erişim:https://doi.org/10.1186/s13018-022-02931-x
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