Circulating plasma fibronectin affects tissue insulin sensitivity, adipocyte differentiation, and transcriptional landscape of adipose tissue in mice

Abstract Plasma fibronectin (pFN) is a hepatocyte‐derived circulating extracellular matrix protein that affects cell morphology, adipogenesis, and insulin signaling of adipocytes in vitro. In this study, we show pFN accrual to adipose tissue and its contribution to tissue homeostasis in mice. Hepato...

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Главные авторы:	Mahdokht Mahmoodi, Elahe Mirzarazi Dahagi, Mir‐Hamed Nabavi, Ylauna C. M. Penalva, Amrita Gosaine, Monzur Murshed, Sandrine Couldwell, Lisa M. Munter, Mari T. Kaartinen
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Wiley 2024-07-01
Серии:	Physiological Reports
Предметы:	adipose tissue beige adipocyte extracellular matrix insulin sensitivity obesity plasma fibronectin
Online-ссылка:	https://doi.org/10.14814/phy2.16152
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