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Genetic influences on alcohol flushing in East Asian populations

Abstract Background Although it is known that variation in the aldehyde dehydrogenase 2 (ALDH2) gene family influences the East Asian alcohol flushing response, knowledge about other genetic variants that affect flushing symptoms is limited. Methods We performed a genome-wide association study meta-...

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Principais autores: Yoonsu Cho, Kuang Lin, Su-Hyun Lee, Canqing Yu, Dan Schmidt Valle, Daniel Avery, Jun Lv, Keumji Jung, Liming Li, George Davey Smith, China Kadoorie Biobank Collaborative Group, Dianjianyi Sun, Zhengming Chen, Iona Y. Millwood, Gibran Hemani, Robin G. Walters
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2023-10-01
Colecção:BMC Genomics
Assuntos:
GWAS
Alcohol
Alcohol flushing
ALDH2
ADH1B
Heritability
Acesso em linha:https://doi.org/10.1186/s12864-023-09721-7
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