Molecular profiling of metastatic breast cancer and target-based therapeutic matching in an Asian tertiary phase I oncology unit

IntroductionMolecular profiling of metastatic breast cancer (MBC) through the widespread use of next-generation sequencing (NGS) has highlighted actionable mutations and driven trials of targeted therapy matched to tumour molecular profiles, with improved outcomes reported using such an approach. He...

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Hlavní autoři:	Robert John Walsh, Rebecca Ong, Seng Wee Cheo, Peter Q.J. Low, Aishwarya Jayagopal, Matilda Lee, Natalie Ngoi, Samuel G. Ow, Andrea L.A. Wong, Siew Eng Lim, Yi Wan Lim, Valerie Heong, Raghav Sundar, Ross A. Soo, Cheng Ean Chee, Wei Peng Yong, Boon Cher Goh, Soo Chin Lee, David S.P. Tan, Joline S.J. Lim
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2024-05-01
Edice:	Frontiers in Oncology
Témata:	breast cancer precision oncology molecular profiling next-generation sequencing (NGS) phase I
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fonc.2024.1342346/full
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