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D’ domain region Arg782-Cys799 of von Willebrand factor contributes to factor VIII binding

In the complex with von Willebrand factor (VWF) factor VIII (FVIII) is protected from rapid clearance from circulation. Although it has been established that the FVIII binding site resides in the N-terminal D’-D3 domains of VWF, detailed information about the amino acid regions that contribute to FV...

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Bibliografski detalji
Glavni autori: Małgorzata A. Przeradzka, Josse van Galen, Eduard H. T. M. Ebberink, Arie J. Hoogendijk, Carmen van der Zwaan, Koen Mertens, Maartje van den Biggelaar, Alexander B. Meijer
Format: Artigo
Jezik:Inglês
Izdano: Ferrata Storti Foundation 2020-06-01
Serija:Haematologica
Online pristup:https://haematologica.org/article/view/9446
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