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Evaluation of Genotoxic Effects of N-Methyl-N-Nitroso-Urea and Etoposide on the Differentiation Potential of MSCs from Umbilical Cord Blood and Bone Marrow

The present study investigates the influence of nitrosamines and etoposide on mesenchymal stromal cells (MSCs) in a differentiation state- and biological age-dependent manner. The genotoxic effects of the agents on both neonatal and adult stem cell populations after treatment, before, or during the...

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Principais autores: Meryem Ouzin, Sebastian Wesselborg, Gerhard Fritz, Gesine Kogler
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-12-01
Serier:Cells
Fag:
mesenchymal stromal cells
osteogenesis
adipogenesis
chondrogenesis
nitrosamines
etoposide
Online adgang:https://www.mdpi.com/2073-4409/13/24/2134
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