DPO production by gut commensals suggests a broader role in bacterial communication and host-microbiome interactions

Abstract The quorum-sensing molecule 3,5-dimethylpyrazine-2-ol (DPO), known for regulating biofilm formation in Vibrio cholerae, has unknown distribution among commensal bacteria. We screened 37 bacterial strains using a validated biosensor and found widespread production. Inoculating mice with high...

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Bibliografische Detailangaben

Hauptverfasser:	Michael Moraskie, Sara Li, Josep-Ramon Codina, Md Harun Or Roshid, Kevin Núño, Gregory O’Connor, Emre Dikici, Sapna Deo, Eleonore Beurel, Sylvia Daunert
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2025-12-01
Schriftenreihe:	npj Biofilms and Microbiomes
Online-Zugang:	https://doi.org/10.1038/s41522-025-00886-5
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