A feasibility study of controlled human infection with intradermal Bacillus Calmette–Guérin (BCG) injection: Pilot BCG controlled human infection model [version 2; peer review: 1 approved, 2 approved with reservations]

Tuberculosis (TB) caused 1.5 million deaths in 2020, making it the leading infectious killer after COVID-19. Bacille Calmette-Guerin (BCG) is the only licensed vaccine against TB but has sub-optimal efficacy against pulmonary TB and reduced effectiveness in regions close to the equator with high bur...

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Những tác giả chính:	Angela Hyder-Wright, Anthony Chirwa, Anthony E. Chirwa, Kondwani Jambo, Ben Morton, Emma Carter, Tinashe Kenny-Nyazika, Dima ElSafadi, Jonathan Gonzalez Sanchez, Gift Chiwala, Giancarlo Biagini, Vincent Yip, Paula Saunderson, Shaun H. Pennington, Christopher Myerscough, Madlen Farrar, Andrea M. Collins, Kelly Convey, Daniela M. Ferreira, Tarsizio Chikaonda, Stephen B. Gordon
Định dạng:	Artigo
Ngôn ngữ:	Inglês
Được phát hành:	Wellcome 2024-06-01
Loạt:	Wellcome Open Research
Những chủ đề:	Human challenge Controlled human infection Human Infection studies Tuberculosis TB eng
Truy cập trực tuyến:	https://wellcomeopenresearch.org/articles/8-424/v2
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