Cerebrovascular involvement in hereditary spherocytosis: observational cohort and case-control MRI study

Abstract Background Anecdotal Literature regarding hereditary spherocytosis, a rare hemolytic anemia, points to an early cerebrovascular involvement that would imply early strict patients’ monitoring and management. However, this issue is under-investigated. Methods Clinical history regarding cerebr...

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Autori principali:	Renzo Manara, Marcella Contieri, Giovanni Librizzi, Teresa Palma, Saverio Scianguetta, Carmine Perna, Annalisa Valentina Villani, Sofia Maria Rosaria Matarese, Margherita Luciano, Alessia Amodio, Maria Agnese Pirozzi, Raffaella Colombatti, Claudia Santoro, Mario Cirillo, Francesco di Salle, Fabrizio Esposito, Silverio Perrotta, Immacolata Tartaglione
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2025-11-01
Serie:	Orphanet Journal of Rare Diseases
Soggetti:	Hereditary spherocytosis Brain MRI and MR-Angiography Moyamoya syndrome Cerebrovascular disease
Accesso online:	https://doi.org/10.1186/s13023-025-04121-4
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