Meta-analysis of 22,710 human microbiome metagenomes defines an oral-to-gut microbial enrichment score and associations with host health and disease

Abstract Large public datasets of the human microbiome now exist but combining them for large-scale analysis is difficult due to a lack of standardization. We developed curatedMetagenomicData (cMD) 3, a uniformly processed collection of over 22,000 human microbiome samples with manually curated meta...

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Autors principals:	Paolo Manghi, Giacomo Antonello, Lucas Schiffer, Davide Golzato, Andres Wokaty, Francesco Beghini, Chloe Mirzayi, Kaelyn Long, Kai Gravel-Pucillo, Gianmarco Piccinno, Samuel David Gamboa-Tuz, Arianna Bonetti, Giacomo D’Amato, Rimsha Azhar, Kelly Eckenrode, Fatima Zohra, Valentina Giunchiglia, Marisa Keller, Anna Pedrotti, Ilya Likhotkin, Shaimaa Elsafoury, Ludwig Geistlinger, Aitor Blanco-Miguez, Andrew Maltez Thomas, Moreno Zolfo, Marcel Ramos, Mireia Valles-Colomer, Sabrina Tamburini, Francesco Asnicar, Heidi E. Jones, Curtis Huttenhower, Vincent Carey, Sean Davis, Edoardo Pasolli, Sehyun Oh, Nicola Segata, Levi Waldron
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2025-12-01
Col·lecció:	Nature Communications
Accés en línia:	https://doi.org/10.1038/s41467-025-66888-1
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