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Bimodal and hysteretic expression in mammalian cells from a synthetic gene circuit.

In order to establish cells and organisms with predictable properties, synthetic biology makes use of controllable, synthetic genetic devices. These devices are used to replace or to interfere with natural pathways. Alternatively, they may be interlinked with endogenous pathways to create artificial...

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Autors principals: Tobias May, Lee Eccleston, Sabrina Herrmann, Hansjörg Hauser, Jorge Goncalves, Dagmar Wirth
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2008-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC2394661?pdf=render
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