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AgTx2-GFP, Fluorescent Blocker Targeting Pharmacologically Important K<sub>v</sub>1.x (x = 1, 3, 6) Channels

The growing interest in potassium channels as pharmacological targets has stimulated the development of their fluorescent ligands (including genetically encoded peptide toxins fused with fluorescent proteins) for analytical and imaging applications. We report on the properties of agitoxin 2 C-termin...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Alexandra L. Primak, Nikita A. Orlov, Steve Peigneur, Jan Tytgat, Anastasia A. Ignatova, Kristina R. Denisova, Sergey A. Yakimov, Mikhail P. Kirpichnikov, Oksana V. Nekrasova, Alexey V. Feofanov
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2023-03-01
Schriftenreihe:Toxins
Schlagworte:
agitoxin 2
GFP
voltage-gated K<sub>v</sub>1 channels
KcsA-K<sub>v</sub>1 channels
affinity
confocal
Online-Zugang:https://www.mdpi.com/2072-6651/15/3/229
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