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Transdermal iontophoresis delivery system for terazosin hydrochloride: an in vitro and in vivo study

This study aimed to construct a transdermal iontophoresis delivery system for terazosin hydrochloride (IDDS-TEH), which included a positive and negative electrode hydrogel prescription. Intact guinea pig skin was used as a model for the skin barrier function, and the current intensity, terazosin hyd...

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Main Authors: Changzhao Jiang, Xiumei Jiang, Xiumin Wang, Jiaxu Shen, Mengjie Zhang, Leilei Jiang, Rui Ma, Tingting Gan, Yingbiao Gong, Jincui Ye, Wenyan Gao
Format: Artigo
Language:Inglês
Published: Taylor & Francis Group 2021-01-01
Series:Drug Delivery
Subjects:
terazosin hydrochloride
iontophoresis
transdermal drug delivery
pharmacokinetics
blood pressure
Online Access:http://dx.doi.org/10.1080/10717544.2021.1889719
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