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Cellular senescence predicts breast cancer risk from benign breast disease biopsy images

Abstract Background Each year, millions of women undergo breast biopsies. Of these, 80% are negative for malignancy but some may be at elevated risk of invasive breast cancer (IBC) due to the presence of benign breast disease (BBD). Cellular senescence plays a complex but poorly understood role in b...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Indra Heckenbach, Rita Peila, Christopher Benz, Sheila Weinmann, Yihong Wang, Mark Powell, Morten Scheibye-Knudsen, Thomas Rohan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2025-03-01
Schriftenreihe:Breast Cancer Research
Schlagworte:
Breast cancer
Benign breast disease
Cellular senescence
Deep learning
Online-Zugang:https://doi.org/10.1186/s13058-025-01993-z
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