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FANCD2 and CtIP Cooperate to Repair DNA Interstrand Crosslinks

The resolution of DNA interstrand crosslinks (ICLs) requires a complex interplay between several processes of DNA metabolism, including the Fanconi anemia (FA) pathway and homologous recombination (HR). FANCD2 monoubiquitination and CtIP-dependent DNA-end resection represent key events in FA and HR...

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Principais autores: Olga Murina, Christine von Aesch, Ufuk Karakus, Lorenza P. Ferretti, Hella A. Bolck, Kay Hänggi, Alessandro A. Sartori
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2014-05-01
Series:Cell Reports
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S2211124714002794
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