CEBPA–double-mutated acute myeloid leukemia displays a unique phenotypic profile: a reliable screening method and insight into biological features

Mutations in CCAAT/enhancer binding protein α (CEBPA) occur in 5–10% of cases of acute myeloid leukemia. CEBPA-double-mutated cases usually bear biallelic N- and C-terminal mutations and are associated with a favorable clinical outcome. Identification of CEBPA mutants is challenging because of the v...

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Autors principals:	Francesco Mannelli, Vanessa Ponziani, Sara Bencini, Maria Ida Bonetti, Matteo Benelli, Ilaria Cutini, Giacomo Gianfaldoni, Barbara Scappini, Fabiana Pancani, Matteo Piccini, Tommaso Rondelli, Roberto Caporale, Anna Maria Grazia Gelli, Benedetta Peruzzi, Marco Chiarini, Erika Borlenghi, Orietta Spinelli, Damiano Giupponi, Pamela Zanghì, Renato Bassan, Alessandro Rambaldi, Giuseppe Rossi, Alberto Bosi
Format:	Artigo
Idioma:	Inglês
Publicat:	Ferrata Storti Foundation 2017-03-01
Col·lecció:	Haematologica
Accés en línia:	https://haematologica.org/article/view/8004
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