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Reduced Insulin-Like Growth Factor-I Effects in the Basal Forebrain of Aging Mouse

It is known that aging is frequently accompanied by a decline in cognition. Furthermore, aging is associated with lower serum IGF-I levels that may contribute to this deterioration. We studied the effect of IGF-I in neurons of the horizontal diagonal band of Broca (HDB) of young (≤6 months old) and...

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Hlavní autoři: Jonathan A. Zegarra-Valdivia, Irene Chaves-Coira, Maria Estrella Fernandez de Sevilla, Laura Martinez-Rachadell, Julio Esparza, Ignacio Torres-Aleman, Angel Nuñez
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021-09-01
Edice:Frontiers in Aging Neuroscience
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fnagi.2021.682388/full
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