Reduction of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant infection by blocking the epidermal growth factor receptor (EGFR) pathway

ABSTRACT The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants presents challenges in global efforts to transition from the pandemic to an endemic stage. The spike protein of the SARS-CoV-2 virus, which is pivotal for cell entry, exhibits significant mutations in its...

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Detalhes bibliográficos

Principais autores:	Yeonju Han, Seunghwan Kim, Taehyun Park, Hyemin Hwang, Sanghee Park, Jimin Kim, Jae-chul Pyun, Misu Lee
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2024-11-01
coleção:	Microbiology Spectrum
Assuntos:	SARS-CoV-2 variants spike protein mutations EGFR pathway osimertinib antiviral therapy
Acesso em linha:	https://journals.asm.org/doi/10.1128/spectrum.01583-24
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