An Efficient Approach for the Design and Synthesis of Antimicrobial Peptide-Peptide Nucleic Acid Conjugates

Peptide-Peptide Nucleic Acid (PNA) conjugates targeting essential bacterial genes have shown significant potential in developing novel antisense antimicrobials. The majority of efforts in this area are focused on identifying different PNA targets and the selection of peptides to deliver the peptide-...

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Bibliographic Details

Main Authors:	Nitin A. Patil, Varsha J. Thombare, Rong Li, Xiaoji He, Jing Lu, Heidi H. Yu, Hasini Wickremasinghe, Kavya Pamulapati, Mohammad A. K. Azad, Tony Velkov, Kade D. Roberts, Jian Li
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2022-03-01
Series:	Frontiers in Chemistry
Subjects:	antisense oligonucleotides peptide nucleic acids antimicrobial agents cell-penetrating peptides conjugation
Online Access:	https://www.frontiersin.org/articles/10.3389/fchem.2022.843163/full
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